Antimicrobial Efficacy of 1,2,3-Triazole-Incorporated Indole-Pyrazolone against Drug-Resistant ESKAPE Pathogens: Design and Synthesis.

Upadhyay DB, Mokariya JA, Patel PJ, Patel SG, Parmar MP, Vala DP, Ferro F, Rajani DP, Narayan M, Kumar J, Banerjee S, Patel HM

The Impact of a Western Diet High in Phosphate on the CKD-MBD in an Alport Syndrome Model.

Williams MJ, Patel HM, Halling CB, Hruska KA

Acetic Acid-Driven One-Pot Synthesis of 4,7-dihydro-[1,2,3]thiadiazolo[5,4-b]pyridine-6-carboxamides and Pharmacological Evaluations.

Bhalodiya SS, Parmar MP, Patel CD, Patel SG, Vala DP, Suresh N, Jayachandran B, Kumar Arumugam M, Narayan M, Patel HM

Repurposing Non-Nucleosidic Reverse Transcriptase Inhibitors (NNRTIs) to Overcome EGFR T790M-Mediated Acquired Resistance in Non-Small Cell Lung Cancer.

Ahmad I, Patel HM

Optimizing Linezolid: Transforming It into a Selective MAO-B Inhibitor via a Toxicity-to-Activity Optimization Approach.

Dhangar MS, Ahmad I, Oh JM, Patil BR, Chinnam S, Sriram D, Kumari J, Mathew B, Sayyed RA, Chaudhari SB, Ansari SA, Rai N, Kim H, Patel HM

Anti-Malarial and Multi-Bioactive Co (II), Cu (II) and Ni (II) Salen Complexes: Synthesis, Characterization and Computational Studies.

Todarwal MA, Sancheti RS, Nikume SR, Patel HM, Bendre RS

One-pot synthesis of tetrahydropyrimidinecarboxamides enabling in vitro anticancer activity: a combinative study with clinically relevant brain-penetrant drugs.

Upadhyay DB, Nogales J, Mokariya JA, Vala RM, Tandon V, Banerjee S, Patel HM

Click-chemistry mediated synthesis of OTBN-1,2,3-Triazole derivatives exhibiting STK33 inhibition with diverse anti-cancer activities.

Vala DP, Dunne Miller A, Atmasidha A, Parmar MP, Patel CD, Upadhyay DB, Bhalodiya SS, GonzĂĄlez-Bakker A, Khan AN, Nogales J, PadrĂłn JM, Banerjee S, Patel HM

Exploring the structural activity relationship of the Osimertinib: A covalent inhibitor of double mutant EGFR(L858R/T790M) tyrosine kinase for the treatment of Non-Small Cell Lung Cancer (NSCLC).

Patil BR, Bhadane KV, Ahmad I, Agrawal YJ, Shimpi AA, Dhangar MS, Patel HM

Alkoxy-functionalised dihydropyrimido[4,5-b]quinolinones enabling anti-proliferative and anti-invasive agents.

Patel SG, Sharma I, Parmar MP, Nogales J, Patel CD, Bhalodiya SS, Vala DP, Shah NV, Banerjee S, Patel HM

Design and Synthesis of the Linezolid Bioisosteres to Resolve the Serotonergic Toxicity Associated with Linezolid.

Girase RT, Ahmad I, Oh JM, Mathew B, Vagolu SK, Tønjum T, Sriram D, Kumari J, Desai NC, Agrawal Y, Kim H, Patel HM

In chronic kidney disease altered cardiac metabolism precedes cardiac hypertrophy.

Williams MJ, Halabi CM, Patel HM, Joseph Z, McCommis K, Weinheimer C, Kovacs A, Lima F, Finck B, Malluche H, Hruska KA

Unpredictable Mixed-Valence Outcomes Induce a Chronic and Reversible Generalized Anxiety-like Phenotype in Male Mice.

Crawford DW, Patel KR, Swiecka A, Bond J, Tiwari A, Plaisted NM, Rednam N, McKeen KM, Patel HM, Sharma P, Roslewicz E, Matzel LD

Indole clubbed 2,4-thiazolidinedione linked 1,2,3-triazole as a potent antimalarial and antibacterial agent against drug-resistant strain and molecular modeling studies.

Upadhyay DB, Mokariya JA, Patel PJ, Patel SG, Das A, Nandi A, Nogales J, More N, Kumar A, Rajani DP, Narayan M, Kumar J, Banerjee S, Sahoo SK, Patel HM

A green bio-organic catalyst (taurine) promoted one-pot synthesis of (R/S)-2-thioxo-3,4-dihydropyrimidine(TDHPM)-5-carboxanilides: chiral investigations using circular dichroism and validation by computational approaches.

Parmar MP, Vala DP, Bhalodiya SS, Upadhyay DB, Patel CD, Patel SG, Gandholi SR, Shaik AH, Miller AD, Nogales J, Banerjee S, PadrĂłn JM, Amri N, Kandukuri NK, Patel HM