Hemorrhagic activity of HF3, a snake venom metalloproteinase: insights from the proteomic analysis of mouse skin and blood plasma.

Paes Leme AF, Sherman NE, Smalley DM, Sizukusa LO, Oliveira AK, Menezes MC, Fox JW, Serrano SM

Generation of a Chinese hamster ovary cell line producing recombinant human glucocerebrosidase.

Novo JB, Morganti L, Moro AM, Paes Leme AF, Serrano SM, Raw I, Ho PL

Insights into the local pathogenesis induced by fish toxins: role of natterins and nattectin in the disruption of cell-cell and cell-extracellular matrix interactions and modulation of cell migration.

Komegae EN, Ramos AD, Oliveira AK, Serrano SM, Lopes-Ferreira M, Lima C

The novel leptospiral surface adhesin Lsa20 binds laminin and human plasminogen and is probably expressed during infection.

Mendes RS, Von Atzingen M, de Morais ZM, Gonçales AP, Serrano SM, Asega AF, Romero EC, Vasconcellos SA, Nascimento AL

Bothrops jararaca venom proteome rearrangement upon neonate to adult transition.

Zelanis A, Tashima AK, Pinto AF, Paes Leme AF, Stuginski DR, Furtado MF, Sherman NE, Ho PL, Fox JW, Serrano SM

High resolution analysis of snake venom metalloproteinase (SVMP) peptide bond cleavage specificity using proteome based peptide libraries and mass spectrometry.

Paes Leme AF, Escalante T, Pereira JG, Oliveira AK, Sanchez EF, GutiĂŠrrez JM, Serrano SM, Fox JW

Disintegrin-like/cysteine-rich domains of the reprolysin HF3: Site-directed mutagenesis reveals essential role of specific residues.

Menezes MC, de Oliveira AK, Melo RL, Lopes-Ferreira M, Rioli V, Balan A, Paes Leme AF, Serrano SM

A Comparative Study of the Outer Membrane Proteome from an Atypical and a Typical Enteropathogenic Escherichia coli.

Taddei CR, Oliveira FF, Piazza RM, Paes Leme AF, Klitzke CF, Serrano SM, Martinez MB, Elias WP, Sant Anna OA

Insularin, a disintegrin from Bothrops insularis venom: inhibition of platelet aggregation and endothelial cell adhesion by the native and recombinant GST-insularin proteins".

Della-Casa MS, Junqueira-de-Azevedo I, Butera D, Clissa PB, Lopes DS, Serrano SM, Pimenta DC, MagalhĂŁes GS, Ho PL, Moura-da-Silva AM

New insights into the structural elements involved in the skin haemorrhage induced by snake venom metalloproteinases.

Oliveira AK, Paes Leme AF, Asega AF, Camargo AC, Fox JW, Serrano SM

Analysis of the ontogenetic variation in the venom proteome/peptidome of Bothrops jararaca reveals different strategies to deal with prey.

Zelanis A, Tashima AK, Rocha MM, Furtado MF, Camargo AC, Ho PL, Serrano SM

NPP-BJ, a nucleotide pyrophosphatase/phosphodiesterase from Bothrops jararaca snake venom, inhibits platelet aggregation.

Santoro ML, Vaquero TS, Paes Leme AF, Serrano SM

Argininosuccinate synthetase is a functional target for a snake venom anti-hypertensive peptide: role in arginine and nitric oxide production.

Guerreiro JR, Lameu C, Oliveira EF, Klitzke CF, Melo RL, Linares E, Augusto O, Fox JW, Lebrun I, Serrano SM, Camargo AC

Simplified procedures for the isolation of HF3, bothropasin, disintegrin-like/cysteine-rich protein and a novel P-I metalloproteinase from Bothrops jararaca venom.

Oliveira AK, Paes Leme AF, Assakura MT, Menezes MC, Zelanis A, Tashima AK, Lopes-Ferreira M, Lima C, Camargo AC, Fox JW, Serrano SM

Timeline of key events in snake venom metalloproteinase research.

Fox JW, Serrano SM