Structural Characteristics of Îą-Synuclein Oligomers.

Cremades N, Chen SW, Dobson CM

Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping.

Bongiovanni MN, Godet J, Horrocks MH, Tosatto L, Carr AR, Wirthensohn DC, Ranasinghe RT, Lee JE, Ponjavic A, Fritz JV, Dobson CM, Klenerman D, Lee SF

The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme.

Ahn M, Hagan CL, Bernardo-Gancedo A, De Genst E, Newby FN, Christodoulou J, Dhulesia A, Dumoulin M, Robinson CV, Dobson CM, Kumita JR

Bifunctional Anti-Non-Amyloid Component Îą-Synuclein Nanobodies Are Protective In Situ.

Butler DC, Joshi SN, Genst E, Baghel AS, Dobson CM, Messer A

β-Synuclein suppresses both the initiation and amplification steps of ι-synuclein aggregation via competitive binding to surfaces.

Brown JW, Buell AK, Michaels TC, Meisl G, Carozza J, Flagmeier P, Vendruscolo M, Knowles TP, Dobson CM, Galvagnion C

Protein Aggregate-Ligand Binding Assays Based on Microfluidic Diffusional Separation.

Zhang Y, Buell AK, MĂźller T, De Genst E, Benesch J, Dobson CM, Knowles TP

Structural basis of synaptic vesicle assembly promoted by Îą-synuclein.

Fusco G, Pape T, Stephens AD, Mahou P, Costa AR, Kaminski CF, Kaminski Schierle GS, Vendruscolo M, Veglia G, Dobson CM, De Simone A

The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.

Crippa V, Cicardi ME, Ramesh N, Seguin SJ, Ganassi M, Bigi I, Diacci C, Zelotti E, Baratashvili M, Gregory JM, Dobson CM, Cereda C, Pandey UB, Poletti A, Carra S

Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of Îą-synuclein aggregation.

Flagmeier P, Meisl G, Vendruscolo M, Knowles TP, Dobson CM, Buell AK, Galvagnion C

Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases.

Evangelisti E, Cascella R, Becatti M, Marrazza G, Dobson CM, Chiti F, Stefani M, Cecchi C

Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies.

Cascella R, Capitini C, Fani G, Dobson CM, Cecchi C, Chiti F

Physical determinants of the self-replication of protein fibrils.

Šarić A, Buell AK, Meisl G, Michaels TCT, Dobson CM, Linse S, Knowles TPJ, Frenkel D

A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimer's disease.

Freer R, Sormanni P, Vecchi G, Ciryam P, Dobson CM, Vendruscolo M

Synthesis of Nonequilibrium Supramolecular Peptide Polymers on a Microfluidic Platform.

Mason TO, Michaels TC, Levin A, Gazit E, Dobson CM, Buell AK, Knowles TP

Towards a structural biology of the hydrophobic effect in protein folding.

Camilloni C, Bonetti D, Morrone A, Giri R, Dobson CM, Brunori M, Gianni S, Vendruscolo M