Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes.

Habchi J, Chia S, Galvagnion C, Michaels TCT, Bellaiche MMJ, Ruggeri FS, Sanguanini M, Idini I, Kumita JR, Sparr E, Linse S, Dobson CM, Knowles TPJ, Vendruscolo M

C-terminal truncation of Îą-synuclein promotes amyloid fibril amplification at physiological pH.

van der Wateren IM, Knowles TPJ, Buell AK, Dobson CM, Galvagnion C

Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-β peptide.

Cohen SIA, Cukalevski R, Michaels TCT, Šarić A, Törnquist M, Vendruscolo M, Dobson CM, Buell AK, Knowles TPJ, Linse S

Optical Structural Analysis of Individual Îą-Synuclein Oligomers.

Varela JA, Rodrigues M, De S, Flagmeier P, Gandhi S, Dobson CM, Klenerman D, Lee SF

Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation.

Michaels TCT, Šarić A, Habchi J, Chia S, Meisl G, Vendruscolo M, Dobson CM, Knowles TPJ

Biophotonics of Native Silk Fibrils.

Shimanovich U, Pinotsi D, Shimanovich K, Yu N, Bolisetty S, Adamcik J, Mezzenga R, Charmet J, Vollrath F, Gazit E, Dobson CM, Schierle GK, Holland C, Kaminski CF, Knowles TPJ

Correction to 'Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species'.

Needham LM, Weber J, Fyfe JWB, Kabia OM, Do DT, Klimont E, Zhang Y, Rodrigues M, Dobson CM, Gandhi S, Bohndiek SE, Snaddon TN, Lee SF

Microfluidic approaches for probing amyloid assembly and behaviour.

Herling TW, Levin A, Saar KL, Dobson CM, Knowles TPJ

The small heat shock protein Hsp27 binds Îą-synuclein fibrils, preventing elongation and cytotoxicity.

Cox D, Whiten DR, Brown JWP, Horrocks MH, San Gil R, Dobson CM, Klenerman D, van Oijen AM, Ecroyd H

Hsp70 Inhibits the Nucleation and Elongation of Tau and Sequesters Tau Aggregates with High Affinity.

Kundel F, De S, Flagmeier P, Horrocks MH, Kjaergaard M, Shammas SL, Jackson SE, Dobson CM, Klenerman D

Microfluidic Diffusion Platform for Characterizing the Sizes of Lipid Vesicles and the Thermodynamics of Protein-Lipid Interactions.

Gang H, Galvagnion C, Meisl G, MĂźller T, Pfammatter M, Buell AK, Levin A, Dobson CM, Mu B, Knowles TPJ

Direct Observation of Oligomerization by Single Molecule Fluorescence Reveals a Multistep Aggregation Mechanism for the Yeast Prion Protein Ure2.

Yang J, Dear AJ, Michaels TCT, Dobson CM, Knowles TPJ, Wu S, Perrett S

On-chip measurements of protein unfolding from direct observations of micron-scale diffusion.

Zhang Y, Yates EV, Hong L, Saar KL, Meisl G, Dobson CM, Knowles TPJ

Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species.

Needham LM, Weber J, Fyfe JWB, Kabia OM, Do DT, Klimont E, Zhang Y, Rodrigues M, Dobson CM, Ghandi S, Bohndiek SE, Snaddon TN, Lee SF

Immunization with Îą-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model.

Villadiego J, Labrador-Garrido A, Franco JM, Leal-Lasarte M, De Genst EJ, Dobson CM, Pozo D, Toledo-Aral JJ, Roodveldt C